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A role for Th17 cells in the immunopathogenesis of atopic dermatitis?
J Invest Dermatol. 2008 Nov;128(11):2569-71
Authors: Di Cesare A, Di Meglio P, Nestle FO
Atopic dermatitis (AD) is a common inflammatory skin disease. Both epidermal barrier dysfunction and immunodysregulation are suggested to influence the pathogenesis of AD. AD has been considered a paradigmatic T helper cell (Th) 2-mediated disease, with a switch to a Th1 cell environment during the chronic phase of the disease. Previously unreported findings now suggest a possible role for Th17 cells as well.
PMID: 18927538 [PubMed - indexed for MEDLINE]
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